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Scientists create potent molecules aimed at treating muscular dystrophy
While RNA is an appealing drug target, small molecules that can actually affect its function have rarely been found. But now scientists have for the first time designed...
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When nerve meets muscle, biglycan seals the deal
In the absence of the protein biglycan, synapses at neuromuscular junctions in mice began to break up about five weeks after birth, according to a new study. Reintroducing...
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Need muscle for a tough spot? Turn to fat stem cells
Stem cells derived from fat have a surprising trick up their sleeves: Encouraged to develop on a stiff surface, they undergo a remarkable transformation toward becoming mature muscle...
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Genes and disease mechanisms behind a common form of muscular dystrophy discovered
Continuing a series of groundbreaking discoveries begun in 2010 about the genetic causes of the third most common form of inherited muscular dystrophy, scientists have identified the genes...
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Enzyme function could help with muscular dystrophy therapies
Researchers have worked out the exact function of an enzyme that is critical for normal muscle structure and is involved in several muscular dystrophies. The findings could be...
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Some muscular dystrophy patients at increased risk for cancer
People who have the most common type of adult muscular dystrophy also have a higher risk of getting cancer, according to a paper published today in the Journal...
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Adult stem cells use special pathways to repair damaged muscle, researchers find
Researchers recently found how even distant satellite cells could help with the repair, and are now learning how the stem cells travel within the tissue. This knowledge could...
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Clinical trial for muscular dystrophy demonstrates safety of customized gene therapy
Researchers have shown that it is safe to cut and paste together different viruses in an effort to create the ultimate vehicle for gene therapy. In a phase...
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Closer to finding treament for Duchenne muscular dystrophy
Academics have made an important breakthrough in the development of a treatment for Duchenne muscular dystrophy (DMD).
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Hope for muscle wasting disease
A health supplement used by bodybuilders could be the key to treating a life-threatening muscular dystrophy affecting tens of thousands of children world-wide, new research shows. The amino...
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X marks the spot: TBL1X gene involved in autism spectrum disorder
Autism spectrum disorder affects about one in 100 children resulting in a range of problems in language, communication and understanding other people's emotional cues, all of which can...
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New insight into fatal spinal disease
Researchers have identified a communication breakdown between nerves and muscles in mice that may provide new insight into the debilitating and fatal human disease known as spinal muscular...
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Study explains why muscles weaken with age and points to possible therapy
Researchers have discovered the biological mechanism behind age-related loss of muscle strength and identified a drug that may help reverse this process.
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Clinical trial of molecular therapy for muscular dystrophy yields significant positive results
A molecular technique has taken one step closer to becoming a treatment for the devastating genetic disease Duchenne muscular dystrophy.
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Crucial role for molecule in muscle development
Researchers have discovered the crucial role of a molecule in skeletal muscle development. The finding could have implications in the future for maintenance of healthy muscle or muscle...
